If you've ever struggled with AOT and packaging misery (NoClassDefFoundException, etc.) while getting Clojure lambdas to work (via any of the libraries like lambada, etc.) you don't need any of that! Instead:
(ns the.namespace)
(deftype Lambda []
:load-ns true
com.amazonaws.services.lambda.runtime.RequestStreamHandler
(handleRequest [this in out context]
YOUR CODE))
Uberjar it up and then point AWS to "the.namespace.Lambda" as the entry class.
(The load-ns bit means load the containing namespace when this deftype's class gets loaded by AWS)